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• Activity deltas table
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Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 1.106

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_+_21495273	2.250
chr1_-_177378801	1.842	NM_001136000 NM_001168239 NM_005158	ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2
chr22_+_21370394	1.777		IGL@	immunoglobulin lambda locus
chr10_+_80498782	1.720	NM_020338	ZMIZ1	zinc finger, MIZ-type containing 1
chr22_+_21464980	1.575
chr2_-_65447267	1.544		SPRED2	sprouty-related, EVH1 domain containing 2
chr2_+_87536174	1.436		NCRNA00152	non-protein coding RNA 152
chr2_+_87536106	1.397		NCRNA00152	non-protein coding RNA 152
chr22_+_21407066	1.374
chr2_-_65447370	1.280	NM_001128210	SPRED2	sprouty-related, EVH1 domain containing 2
chr17_+_72958330	1.240		SEPT9	septin 9
chr22_+_21393107	1.203		IGLJ3	immunoglobulin lambda joining 3
chr1_+_181421984	1.193		LAMC2	laminin, gamma 2
chr17_+_72958207	1.187	NM_001113496	SEPT9	septin 9
chr7_-_104696678	1.167	NM_182691	SRPK2	SRSF protein kinase 2
chr1_+_15128882	1.139	NM_001018001	KAZN	kazrin, periplakin interacting protein
chr17_+_22823151	1.120	NM_014238	KSR1	kinase suppressor of ras 1
chr1_+_181421796	1.065	NM_005562 NM_018891	LAMC2	laminin, gamma 2
chr1_+_154351082	1.054	NM_005572 NM_170707 NM_170708	LMNA	lamin A/C
chr22_+_21053972	1.027
chr22_+_21116283	0.989
chr12_+_10256682	0.988	NM_031412	GABARAPL1	GABA(A) receptor-associated protein like 1
chr20_-_51633042	0.968	NM_006526	ZNF217	zinc finger protein 217
chr6_-_169392771	0.924
chr6_+_47774247	0.908	NM_153838	GPR115	G protein-coupled receptor 115
chr17_+_23393744	0.887	NM_016231	NLK	nemo-like kinase
chr8_-_38505331	0.881	NM_207412	C8orf86	chromosome 8 open reading frame 86
chr1_-_45045543	0.848	NM_001013632	TCTEX1D4	Tctex1 domain containing 4
chr22_+_21552897	0.842		LOC100290481	immunoglobulin lambda light chain-like
chr1_+_36394338	0.834	NM_018067	MAP7D1	MAP7 domain containing 1
chr9_+_102231616	0.822	NM_001198806	C9orf30	chromosome 9 open reading frame 30
chr19_+_54068373	0.803		PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr18_+_54039779	0.791		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr7_-_50740491	0.788	NM_001001550	GRB10	growth factor receptor-bound protein 10
chr1_+_154351162	0.784		LMNA	lamin A/C
chr12_+_94200306	0.784		VEZT	vezatin, adherens junctions transmembrane protein
chr4_+_154397975	0.780		TRIM2	tripartite motif containing 2
chr22_+_20899155	0.769
chr15_-_53996597	0.761	NM_198400	NEDD4	neural precursor cell expressed, developmentally down-regulated 4
chr17_+_23394062	0.753		NLK	nemo-like kinase
chr18_+_54039818	0.750		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr19_+_54068300	0.741		PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr18_+_54039730	0.738	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr1_-_94779727	0.731	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr7_+_28692122	0.728	NM_001011666	CREB5	cAMP responsive element binding protein 5
chr20_-_35586366	0.728	NM_001167823	BLCAP	bladder cancer associated protein
chr1_+_154351200	0.727		LMNA	lamin A/C
chr13_+_96726415	0.716		MBNL2	muscleblind-like 2 (Drosophila)
chr11_-_8695974	0.712		ST5	suppression of tumorigenicity 5
chr18_+_3443771	0.708	NM_173211	TGIF1	TGFB-induced factor homeobox 1
chr22_+_21079355	0.695
chr1_+_181422016	0.694		LAMC2	laminin, gamma 2
chr13_+_96726197	0.688		MBNL2	muscleblind-like 2 (Drosophila)
chr10_+_24795446	0.682		KIAA1217	KIAA1217
chr13_-_98757634	0.673	NM_004951	GPR183	G protein-coupled receptor 183
chr10_+_24795465	0.672		KIAA1217	KIAA1217
chr7_-_33047042	0.672	NM_001166118 NM_016489	NT5C3	5'-nucleotidase, cytosolic III
chr18_+_19706979	0.662	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr1_-_205290921	0.661	NM_018566	YOD1	YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr22_+_21340757	0.659
chr1_-_36589744	0.654
chr5_+_72179685	0.643	NM_153188	TNPO1	transportin 1
chr17_-_30414789	0.632	NM_001017368	RFFL	ring finger and FYVE-like domain containing 1
chr22_+_21042091	0.617		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr17_+_55269974	0.608
chr2_-_55053398	0.606
chr16_+_51690564	0.588		CHD9	chromodomain helicase DNA binding protein 9
chr11_+_64950402	0.581
chr5_+_72179749	0.581		TNPO1	transportin 1
chr8_+_126511739	0.578	NM_025195	TRIB1	tribbles homolog 1 (Drosophila)
chr10_-_49152918	0.568	NM_001018071	FRMPD2	FERM and PDZ domain containing 2
chr1_+_28637247	0.563	NM_023923	PHACTR4	phosphatase and actin regulator 4
chr5_+_177473071	0.552	NM_015111	N4BP3	NEDD4 binding protein 3
chr1_+_36394044	0.550		MAP7D1	MAP7 domain containing 1
chr15_+_84021271	0.541	NM_144767	AKAP13	A kinase (PRKA) anchor protein 13
chr4_+_108965167	0.541	NM_001136258	SGMS2	sphingomyelin synthase 2
chr9_-_34652629	0.539	NM_006664	CCL27	chemokine (C-C motif) ligand 27
chr3_-_188936941	0.532	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr21_-_34820916	0.530	NM_203418	RCAN1	regulator of calcineurin 1
chr2_+_62787534	0.516	NM_001142614	EHBP1	EH domain binding protein 1
chr21_+_29593098	0.515		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr4_+_169989680	0.515	NM_001166110	PALLD	palladin, cytoskeletal associated protein
chr10_+_121400926	0.511		BAG3	BCL2-associated athanogene 3
chr8_+_26206648	0.509	NM_001177591	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr19_-_61039939	0.508	NM_145007	NLRP11	NLR family, pyrin domain containing 11
chr1_-_111908085	0.503	NM_001081976	ADORA3	adenosine A3 receptor
chr19_-_45623720	0.500	NM_013376	SERTAD1	SERTA domain containing 1
chr3_-_25658829	0.495		TOP2B	topoisomerase (DNA) II beta 180kDa
chr6_+_12398514	0.493	NM_001168319 NM_001955	EDN1	endothelin 1
chr16_+_72888161	0.489	NM_002811	PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr12_+_119456538	0.487		RNF10	ring finger protein 10
chr19_+_3317575	0.485		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr1_-_232810111	0.481		IRF2BP2	interferon regulatory factor 2 binding protein 2
chr10_-_105228986	0.480	NM_001129742	CALHM3	calcium homeostasis modulator 3
chr10_+_123862430	0.479		TACC2	transforming, acidic coiled-coil containing protein 2
chr2_+_170074457	0.473	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr12_+_63084317	0.471	NM_007235	XPOT	exportin, tRNA (nuclear export receptor for tRNAs)
chr3_+_185520744	0.469	NM_004953	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr16_+_72888231	0.466		PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr21_+_29593088	0.466	NM_001186	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr3_+_185521139	0.464		EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr1_+_221966849	0.463		CAPN2	calpain 2, (m/II) large subunit
chr11_+_62405736	0.462		SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr10_+_121400881	0.459		BAG3	BCL2-associated athanogene 3
chr19_+_3317589	0.459		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr17_-_3407780	0.457		TRPV3	transient receptor potential cation channel, subfamily V, member 3
chr1_+_221966835	0.454		CAPN2	calpain 2, (m/II) large subunit
chr3_+_185377341	0.454		AP2M1	adaptor-related protein complex 2, mu 1 subunit
chr1_-_242073094	0.452	NM_005465 NM_181690	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr12_+_109203412	0.452	NM_001135765 NM_001681 NM_170665	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr19_-_17432724	0.451	NM_138454	NXNL1	nucleoredoxin-like 1
chr7_-_158304062	0.450		ESYT2	extended synaptotagmin-like protein 2
chr11_-_33701073	0.447	NM_001127227	CD59	CD59 molecule, complement regulatory protein
chr6_-_41781655	0.445		TFEB	transcription factor EB
chr6_-_116799548	0.443		LOC100287467	hypothetical LOC100287467
chr16_-_45562840	0.442		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr12_-_52281050	0.439	NM_001130059	ATF7	activating transcription factor 7
chr17_-_24069299	0.439	NM_001142624 NM_001142625 NM_001144943	RAB34	RAB34, member RAS oncogene family
chr10_+_121400741	0.435	NM_004281	BAG3	BCL2-associated athanogene 3
chr19_+_59107802	0.434	NM_031896	CACNG7	calcium channel, voltage-dependent, gamma subunit 7
chr17_+_65582981	0.431	NM_018658 NM_170741	KCNJ16	potassium inwardly-rectifying channel, subfamily J, member 16
chr6_-_35804337	0.427	NM_001145775	FKBP5	FK506 binding protein 5
chr16_+_68157370	0.426		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr10_+_70745615	0.425	NM_033496	HK1	hexokinase 1
chr6_+_107066422	0.421	NM_001624	AIM1	absent in melanoma 1
chr19_+_45564549	0.421		PLD3	phospholipase D family, member 3
chr4_+_88076418	0.420
chr18_+_59705918	0.418	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr11_+_65026382	0.417
chr22_+_20715340	0.415
chr1_+_221966684	0.414	NM_001748	CAPN2	calpain 2, (m/II) large subunit
chr10_+_121401061	0.413		BAG3	BCL2-associated athanogene 3
chr21_+_29439768	0.409		C21orf7	chromosome 21 open reading frame 7
chr19_+_3317536	0.409	NM_005597	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr1_+_17507276	0.407	NM_012387	PADI4	peptidyl arginine deiminase, type IV
chr9_-_90456824	0.406	NM_001100111	LOC286238	hypothetical protein LOC286238
chr6_+_138230045	0.399	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr3_-_39209075	0.398	NM_194293 NM_001198621	XIRP1	xin actin-binding repeat containing 1
chr10_+_121401032	0.397		BAG3	BCL2-associated athanogene 3
chr1_+_211291334	0.396		RPS6KC1	ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr21_+_37714470	0.396	NM_130438 NM_001396	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr2_-_73170290	0.392		RAB11FIP5	RAB11 family interacting protein 5 (class I)
chr3_+_192529567	0.391	NM_174908 NM_178335	CCDC50	coiled-coil domain containing 50
chr3_+_185377430	0.387		AP2M1	adaptor-related protein complex 2, mu 1 subunit
chr11_+_67107852	0.386		GSTP1	glutathione S-transferase pi 1
chr6_+_163904564	0.386		QKI	quaking homolog, KH domain RNA binding (mouse)
chr18_+_59295123	0.386	NM_002639	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr8_-_13018123	0.385	NM_001164271	DLC1	deleted in liver cancer 1
chr19_-_56215084	0.379	NM_002776 NM_001077500	KLK10	kallikrein-related peptidase 10
chr10_-_31328426	0.378	NM_001143769	ZNF438	zinc finger protein 438
chr1_+_221966951	0.378		CAPN2	calpain 2, (m/II) large subunit
chr21_+_31953803	0.375	NM_000454	SOD1	superoxide dismutase 1, soluble
chr8_-_95289945	0.373	NM_004063	CDH17	cadherin 17, LI cadherin (liver-intestine)
chr5_+_145297490	0.373		SH3RF2	SH3 domain containing ring finger 2
chr3_+_142569988	0.372		ZBTB38	zinc finger and BTB domain containing 38
chr12_+_13240983	0.372		EMP1	epithelial membrane protein 1
chr17_+_55051818	0.369	NM_004859	CLTC	clathrin, heavy chain (Hc)
chr1_-_45249603	0.368	NM_024602	HECTD3	HECT domain containing 3
chr12_+_109203526	0.367		ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr10_+_121401076	0.366		BAG3	BCL2-associated athanogene 3
chr3_+_133855979	0.365	NM_198329	UBA5	ubiquitin-like modifier activating enzyme 5
chr6_+_131190237	0.363	NM_001195597	LOC285733	hypothetical LOC285733
chr12_+_13240987	0.363		EMP1	epithelial membrane protein 1
chr1_+_151025376	0.362	NM_178353	LCE1E	late cornified envelope 1E
chr1_+_211291274	0.362		RPS6KC1	ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr9_+_131974506	0.361	NM_014286	NCS1	neuronal calcium sensor 1
chr21_+_29592984	0.361		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr3_-_158703821	0.360	NM_001167911 NM_001167912	VEPH1	ventricular zone expressed PH domain homolog 1 (zebrafish)
chr6_+_41712907	0.360		MDFI	MyoD family inhibitor
chr7_+_150319076	0.358	NM_000603	NOS3	nitric oxide synthase 3 (endothelial cell)
chr7_+_30927439	0.358	NM_001185060 NM_001185061 NM_001185062	AQP1	aquaporin 1 (Colton blood group)
chr4_+_183302105	0.358		ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)
chr17_-_24068759	0.358	NM_001144942 NM_031934	RAB34	RAB34, member RAS oncogene family
chr5_+_179180447	0.356	NM_003900	SQSTM1	sequestosome 1
chr15_+_49909147	0.355		TMOD3	tropomodulin 3 (ubiquitous)
chr2_+_30223372	0.355		YPEL5	yippee-like 5 (Drosophila)
chr10_-_14090459	0.354		FRMD4A	FERM domain containing 4A
chr14_+_102870913	0.353	NM_183004	EIF5	eukaryotic translation initiation factor 5
chr7_-_128330615	0.351		KCP	kielin/chordin-like protein
chrX_-_76824726	0.351		ATRX	alpha thalassemia/mental retardation syndrome X-linked
chr5_+_179180509	0.347		SQSTM1	sequestosome 1
chr2_+_30223253	0.345	NM_001127399 NM_001127400 NM_001127401 NM_016061	YPEL5	yippee-like 5 (Drosophila)
chr17_-_3408038	0.344	NM_145068	TRPV3	transient receptor potential cation channel, subfamily V, member 3
chr7_-_98983924	0.342		FAM200A	family with sequence similarity 200, member A
chr22_+_20880159	0.342		IGLV6-57	immunoglobulin lambda variable 6-57
chr10_+_17310475	0.342		VIM	vimentin
chr12_+_106498763	0.342	NM_001017523	BTBD11	BTB (POZ) domain containing 11
chr10_+_82163568	0.336		C10orf58	chromosome 10 open reading frame 58
chr3_+_19963865	0.334		RAB5A	RAB5A, member RAS oncogene family
chr3_-_195571748	0.330	NM_001135057 NM_130830	LRRC15	leucine rich repeat containing 15
chr11_-_82460531	0.330	NM_014488	RAB30	RAB30, member RAS oncogene family
chr14_+_19414230	0.329	NM_001005501	OR4K2	olfactory receptor, family 4, subfamily K, member 2
chr5_+_179180517	0.329		SQSTM1	sequestosome 1
chr1_-_156923111	0.327	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_-_149847718	0.326		ZC3H12D	zinc finger CCCH-type containing 12D
chr1_-_45249554	0.326		HECTD3	HECT domain containing 3
chr10_+_17310263	0.325	NM_003380	VIM	vimentin
chr2_+_27358800	0.321	NM_032546 NM_187841	TRIM54	tripartite motif containing 54
chr2_+_113591940	0.321	NM_000577 NM_173841 NM_173843	IL1RN	interleukin 1 receptor antagonist
chr22_+_21094094	0.320

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.19	2.71e-04	GO:0050794	regulation of cellular process
1.17	5.28e-04	GO:0065007	biological regulation
1.39	6.88e-04	GO:0048519	negative regulation of biological process
1.41	7.51e-04	GO:0048523	negative regulation of cellular process
1.18	1.09e-03	GO:0050789	regulation of biological process
1.54	1.82e-02	GO:0042981	regulation of apoptosis
1.53	1.87e-02	GO:0010941	regulation of cell death
1.53	2.64e-02	GO:0043067	regulation of programmed cell death

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
3.29	1.28e-02	GO:0000502	proteasome complex
2.31	4.08e-02	GO:0005769	early endosome

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.18	6.85e-05	GO:0005515	protein binding